Reporter Virus Tools to Combat Current Viral Threats and the Next Pandemic


The COVID-19 pandemic has brought virology to the forefront of many research programs. But how do we get ahead of the next viral threat? Limited commercial labs are licensed to conduct research using BSL-3 or BSL-4 pathogens. However, reporter virus tools such as ready-to-use Reporter Virus Particles (RVPs, i.e., pseudoviruses) have enabled virus research in a BSL-2 environment, allowing testing of sera and antibodies in high-throughput, safe neutralization assays to accelerate virology research.

In this GEN webinar, one of our distinguished speakers, Dr. Hayley Crawford, will discuss Integral Molecular’s broad catalog of RVPs, including influenza A and B, Marburg virus, and the latest variants of SARS-CoV-2. Moreover, she will discuss Integral Molecular’s expertise in custom RVP projects. Additionally, panelists Dr. Sheila Keating and Dr. Natalie Anosova will describe how Integral Molecular’s extensive collection of SARS-CoV-2 variant RVPs enabled them to meet the most recent FDA guidance for variant testing of vaccines and therapeutic antibodies.

Video contents

Jeff Buguliskis, PhD, Technical Editor, Genetic Engineering & Biotechnology News

Haley Crawford, PhD, Virology Research & Applications Specialist, Integral Molecular

Dr. Crawford discusses how you can facilitate safe and reproducible neutralization assays using RVPs.

Sheila M. Keating, PhD, MSPH, Vice President of Immunology, GigaGen

Dr. Keating describes how GigaGen used RVP neutralization assays in developing an antibody therapeutic against SARS-CoV-2.

Natalie Anosova, PhD, Director Immunology, Head of Preclinical Immunobiology, Sanofi

Dr. Anosova describes how Sanofi used RVPs in the development of a SARS-CoV-2 vaccine candidate.

Related publications

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